For research use only. Not for therapeutic Use.
RU-302（Cat No.:I018132）is a small-molecule inhibitor that selectively targets RGS4 (Regulator of G-protein Signaling 4), a protein that accelerates GTP hydrolysis on Gα subunits, thereby modulating GPCR signaling. By blocking RGS4 activity, RU-302 prolongs G-protein signaling, allowing researchers to investigate its physiological and pathological roles in the nervous system, cardiovascular function, and pain modulation. This compound is widely used in mechanistic studies of GPCR regulation and signal transduction. RU-302 provides a valuable pharmacological tool for exploring therapeutic opportunities involving RGS protein modulation.
| CAS Number | 1182129-77-6 |
| Synonyms | [2-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]phenyl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone |
| Molecular Formula | C24H24F3N3O2S |
| Purity | ≥95% |
| IUPAC Name | [2-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]phenyl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone |
| InChI | InChI=1S/C24H24F3N3O2S/c1-16-21(17(2)32-28-16)15-33-22-9-4-3-8-20(22)23(31)30-12-10-29(11-13-30)19-7-5-6-18(14-19)24(25,26)27/h3-9,14H,10-13,15H2,1-2H3 |
| InChIKey | IZHRNXCFYZERFF-UHFFFAOYSA-N |
| SMILES | CC1=C(C(=NO1)C)CSC2=CC=CC=C2C(=O)N3CCN(CC3)C4=CC=CC(=C4)C(F)(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
