For research use only. Not for therapeutic Use.
RS 09 TFA（Cat No.:I045793）is a synthetic lipopeptide and potent agonist of Toll-like receptor 4 (TLR4), designed as an immunostimulatory agent with improved activity and reduced toxicity compared to bacterial lipopolysaccharides (LPS). By activating TLR4 signaling, RS 09 induces innate immune responses, including cytokine production and dendritic cell maturation, making it a valuable tool in immunology and vaccine research. The trifluoroacetate (TFA) salt improves solubility and handling. RS 09 TFA is widely used to study innate immune activation, host–pathogen interactions, and the development of vaccine adjuvants and immunotherapies.
| CAS Number | 1449566-36-2 |
| Synonyms | (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-1-[(2S)-2-aminopropanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoic acid;2,2,2-trifluoroacetic acid |
| Molecular Formula | C33H50F3N9O11 |
| Purity | ≥95% |
| IUPAC Name | (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-1-[(2S)-2-aminopropanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoic acid;2,2,2-trifluoroacetic acid |
| InChI | InChI=1S/C31H49N9O9.C2HF3O2/c1-16(2)11-20(27(44)38-22(14-41)31(48)49)36-25(42)18(4)35-26(43)21(12-19-13-33-15-34-19)37-28(45)23-7-5-9-39(23)30(47)24-8-6-10-40(24)29(46)17(3)32;3-2(4,5)1(6)7/h13,15-18,20-24,41H,5-12,14,32H2,1-4H3,(H,33,34)(H,35,43)(H,36,42)(H,37,45)(H,38,44)(H,48,49);(H,6,7)/t17-,18-,20-,21-,22-,23-,24-;/m0./s1 |
| InChIKey | JEJDMAALCYLRNZ-QVWBAPIKSA-N |
| SMILES | C[C@@H](C(=O)N1CCC[C@H]1C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC3=CN=CN3)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)O)N.C(=O)(C(F)(F)F)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
