Rp-cAMPS sodium salt

• CAT Number: I014837
• CAS Number: 142439-94-9
• Molecular Formula: C10H11N5NaO5PS
• Molecular Weight: 367.25
• Purity: ≥95%
• Synonyms: sodium;(4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-2-oxido-2-sulfanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
• InChI: InChI=1S/C10H12N5O5PS.Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(19-10)1-18-21(17,22)20-7;/h2-4,6-7,10,16H,1H2,(H,17,22)(H2,11,12,13);/q;+1/p-1/t4-,6-,7-,10-,21?;/m1./s1
• InChIKey: YTUKZYORDGLGPR-NVGWRVNNSA-M
• SMILES: C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)OP(=S)(O1)[O-].[Na+]

Rp-cAMPS sodium salt（Cat No.:I014837）is a synthetic analog of cyclic adenosine monophosphate (cAMP) that functions as a selective, competitive inhibitor of cAMP-dependent protein kinase (PKA). By binding to the regulatory subunit of PKA without activating it, Rp-cAMPS blocks cAMP-mediated signaling, allowing precise study of PKA-dependent pathways. This reagent is widely used in cell signaling research to dissect the role of cAMP/PKA in processes such as metabolism, gene expression, synaptic plasticity, and cardiac function. The sodium salt form ensures stability and solubility for reliable biochemical and cellular studies.