For research use only. Not for therapeutic Use.
Roxatidine（Cat No.:I035708）is a histamine H2 receptor antagonist used to reduce gastric acid secretion, primarily in the treatment of peptic ulcers, gastritis, and gastroesophageal reflux disease (GERD). It works by competitively inhibiting histamine binding at H2 receptors on parietal cells in the stomach lining, thereby suppressing basal and stimulated acid production. Roxatidine offers a favorable pharmacokinetic profile, with a longer duration of action and fewer central nervous system effects compared to earlier H2 antagonists. It is commonly administered as Roxatidine acetate hydrochloride, a prodrug that is rapidly converted to the active form in vivo.
| CAS Number | 78273-80-0 |
| Synonyms | 2-hydroxy-N-[3-[3-(piperidin-1-ylmethyl)phenoxy]propyl]acetamide |
| Molecular Formula | C17H26N2O3 |
| Purity | ≥95% |
| IUPAC Name | 2-hydroxy-N-[3-[3-(piperidin-1-ylmethyl)phenoxy]propyl]acetamide |
| InChI | InChI=1S/C17H26N2O3/c20-14-17(21)18-8-5-11-22-16-7-4-6-15(12-16)13-19-9-2-1-3-10-19/h4,6-7,12,20H,1-3,5,8-11,13-14H2,(H,18,21) |
| InChIKey | BCCREUFCSIMJFS-UHFFFAOYSA-N |
| SMILES | C1CCN(CC1)CC2=CC(=CC=C2)OCCCNC(=O)CO |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
