Roxadustat-d5

• CAT Number: I035704
• CAS Number: 2043026-13-5
• Molecular Formula: C19H11D5N2O5
• Molecular Weight: 357.37
• Purity: ≥95%
• Synonyms: 2-[[4-hydroxy-1-methyl-7-(2,3,4,5,6-pentadeuteriophenoxy)isoquinoline-3-carbonyl]amino]acetic acid
• InChI: InChI=1S/C19H16N2O5/c1-11-15-9-13(26-12-5-3-2-4-6-12)7-8-14(15)18(24)17(21-11)19(25)20-10-16(22)23/h2-9,24H,10H2,1H3,(H,20,25)(H,22,23)/i2D,3D,4D,5D,6D
• InChIKey: YOZBGTLTNGAVFU-VIQYUKPQSA-N
• SMILES: [2H]C1=C(C(=C(C(=C1[2H])[2H])OC2=CC3=C(N=C(C(=C3C=C2)O)C(=O)NCC(=O)O)C)[2H])[2H]

Roxadustat-d5（Cat No.:I035704）is a deuterated form of Roxadustat, an oral hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used in the treatment of anemia associated with chronic kidney disease (CKD). The deuteration at the 5-position allows for enhanced stability and precise tracking in metabolic studies. Roxadustat works by stimulating the body’s natural production of erythropoietin, promoting red blood cell production without the need for exogenous erythropoiesis-stimulating agents. Roxadustat-d5 is primarily utilized in research to study pharmacokinetics, metabolic pathways, and the efficacy of Roxadustat in various therapeutic settings.