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Rotigotine Hydrochloride

Rotigotine Hydrochloride

  • CAT Number: I001020
  • CAS Number: 125572-93-2
  • Molecular Formula: C19H26ClNOS
  • Molecular Weight: 351.93
  • Purity: ≥95%
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<p style=/line-height:25px/>Rotigotine Hcl is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively.<br>IC50 value: 13/0.71 nM (D2/D3) [1]<br>Target: D2 and D3 receptor<br>Rotigotine also has significant affinity for 5-HT1A and adrenergic α2B receptors. Rotigotine exhibits antiparkinsonian acitivity.</p>

Catalog Number I001020
CAS Number 125572-93-2
Molecular Formula

C19H26ClNOS

Purity 95%
Target 5-HT Receptor
Solubility 10 mM in water ; 100 mM in DMSO
Storage Store at -20°C
IC50 13/0.71 nM (D2/D3) [1]
Reference

<p style=/line-height:25px/>
<br>[1]. Belluzzi et al (2004) N-0923, a selective dopamine D2 receptor agonist, is efficacious in rat and monkey models of Parkinson/’s disease. Mov.disord. 9 147.
</p>

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