For research use only. Not for therapeutic Use.
Rosiglitazone hydrochloride（Cat No.:A001039）is an oral antidiabetic agent belonging to the thiazolidinedione (TZD) class and functions as a selective agonist of peroxisome proliferator–activated receptor gamma (PPARγ). By enhancing insulin sensitivity in adipose tissue, muscle, and liver, it improves glucose uptake and reduces hepatic glucose production, thereby lowering blood sugar levels in type 2 diabetes. Beyond glycemic control, rosiglitazone modulates lipid metabolism and inflammatory pathways. The hydrochloride salt form provides improved stability and handling. In research, it is widely used to study metabolic regulation, insulin resistance, and cardiovascular risk mechanisms.
| CAS Number | 302543-62-0 |
| Synonyms | 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydrochloride |
| Molecular Formula | C18H20ClN3O3S |
| Purity | ≥95% |
| IUPAC Name | 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydrochloride |
| InChI | InChI=1S/C18H19N3O3S.ClH/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15;/h2-9,15H,10-12H2,1H3,(H,20,22,23);1H |
| InChIKey | XRSCTTPDKURIIJ-UHFFFAOYSA-N |
| SMILES | CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
