For research use only. Not for therapeutic Use.
ROC-0929（Cat No.:I045144）is an investigational small-molecule inhibitor targeting Rho-associated coiled-coil containing protein kinase 2 (ROCK2), a key regulator of cytoskeletal dynamics, cell migration, and immune responses. By selectively inhibiting ROCK2, ROC-0929 modulates downstream signaling pathways involved in inflammation, fibrosis, and neurodegeneration. It is being explored for therapeutic potential in autoimmune diseases, including multiple sclerosis and psoriasis, as well as fibrotic and cardiovascular conditions. ROC-0929 offers advantages in tissue-selective immunomodulation with reduced off-target effects. Supplied for research into ROCK signaling, cytoskeletal regulation, and targeted immunotherapy.
| CAS Number | 1048660-43-0 |
| Synonyms | N-(benzenesulfonyl)-2-[1-benzyl-2-(2-methylpropyl)-3-oxamoylindol-4-yl]oxypropanamide |
| Molecular Formula | C30H31N3O6S |
| Purity | ≥95% |
| IUPAC Name | N-(benzenesulfonyl)-2-[1-benzyl-2-(2-methylpropyl)-3-oxamoylindol-4-yl]oxypropanamide |
| InChI | InChI=1S/C30H31N3O6S/c1-19(2)17-24-27(28(34)29(31)35)26-23(33(24)18-21-11-6-4-7-12-21)15-10-16-25(26)39-20(3)30(36)32-40(37,38)22-13-8-5-9-14-22/h4-16,19-20H,17-18H2,1-3H3,(H2,31,35)(H,32,36) |
| InChIKey | REUKAAAAEHWGGM-UHFFFAOYSA-N |
| SMILES | CC(C)CC1=C(C2=C(N1CC3=CC=CC=C3)C=CC=C2OC(C)C(=O)NS(=O)(=O)C4=CC=CC=C4)C(=O)C(=O)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
