RO27-3225 TFA

• CAT Number: I045905
• CAS Number: 1373926-49-8
• Molecular Formula: C41H53F3N12O8
• Molecular Weight: 898.93
• Purity: ≥95%
• IUPAC Name: (2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)-methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-2-(butanoylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanamide;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C39H52N12O6.C2HF3O2/c1-3-10-34(53)47-31(19-26-21-43-23-46-26)37(56)49-30(17-24-11-5-4-6-12-24)36(55)48-29(15-9-16-44-39(41)42)35(54)50-32(38(57)51(2)22-33(40)52)18-25-20-45-28-14-8-7-13-27(25)28;3-2(4,5)1(6)7/h4-8,11-14,20-21,23,29-32,45H,3,9-10,15-19,22H2,1-2H3,(H2,40,52)(H,43,46)(H,47,53)(H,48,55)(H,49,56)(H,50,54)(H4,41,42,44);(H,6,7)/t29-,30-,31-,32-;/m0./s1
• InChIKey: XBNXUPIBUGBMCO-WYDLTDSDSA-N
• SMILES: CCCC(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N(C)CC(=O)N.C(=O)(C(F)(F)F)O

RO27-3225 TFA（Cat No.:I045905）is a synthetic peptide analog of α-melanocyte–stimulating hormone (α-MSH), supplied as a trifluoroacetate (TFA) salt. It acts as a potent and selective agonist of melanocortin receptors, particularly MC3R and MC4R, which are involved in regulating energy balance, feeding behavior, and inflammation. By activating these receptors, RO27-3225 has been studied in metabolic and neuroendocrine research for its effects on appetite suppression, weight regulation, and anti-inflammatory activity. This compound is a valuable tool for exploring melanocortin receptor biology, peptide therapeutics, and metabolic disease mechanisms.