For research use only. Not for therapeutic Use.
RO0270608（Cat No.:I044619）is a potent and selective small-molecule inhibitor targeting the HIV-1 fusion process, specifically interfering with the gp41-mediated membrane fusion between the virus and host cell. By blocking this critical step in viral entry, RO0270608 prevents HIV-1 from infecting host T cells, offering a valuable mechanism for antiviral intervention. It has demonstrated strong efficacy in preclinical studies, with potential utility in combination antiretroviral therapy. RO0270608 is primarily used in virology research to explore fusion inhibition strategies and to support the development of novel therapeutics against HIV and related retroviruses.
| CAS Number | 220846-33-3 |
| Synonyms | (2S)-2-[(2-chloro-6-methylbenzoyl)amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid |
| Molecular Formula | C24H19Cl3N2O4 |
| Purity | ≥95% |
| IUPAC Name | (2S)-2-[(2-chloro-6-methylbenzoyl)amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid |
| InChI | InChI=1S/C24H19Cl3N2O4/c1-13-4-2-5-16(25)20(13)22(30)29-19(24(32)33)12-14-8-10-15(11-9-14)28-23(31)21-17(26)6-3-7-18(21)27/h2-11,19H,12H2,1H3,(H,28,31)(H,29,30)(H,32,33)/t19-/m0/s1 |
| InChIKey | JTVWJXUGGJTGDA-IBGZPJMESA-N |
| SMILES | CC1=C(C(=CC=C1)Cl)C(=O)N[C@@H](CC2=CC=C(C=C2)NC(=O)C3=C(C=CC=C3Cl)Cl)C(=O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
