For research use only. Not for therapeutic Use.
RO-3（Cat No.:I010670）is a potent small-molecule inhibitor targeting the RNA-binding protein Musashi-2 (MSI2), a regulator of stem cell maintenance, differentiation, and oncogenic signaling. By disrupting MSI2’s interaction with its RNA targets, RO-3 impairs the expression of genes involved in leukemogenesis and tumor progression. It has shown efficacy in preclinical models of acute myeloid leukemia (AML) and other cancers where MSI2 is overexpressed. RO-3 offers a novel therapeutic approach by targeting post-transcriptional gene regulation, making it a valuable tool for studying RNA-binding protein function and a promising lead for cancer drug development.
| CAS Number | 1026582-88-6 |
| Synonyms | 5-[(4,5-dimethoxy-2-propan-2-ylphenyl)methyl]pyrimidine-2,4-diamine |
| Molecular Formula | C16H22N4O2 |
| Purity | ≥95% |
| IUPAC Name | 5-[(4,5-dimethoxy-2-propan-2-ylphenyl)methyl]pyrimidine-2,4-diamine |
| InChI | InChI=1S/C16H22N4O2/c1-9(2)12-7-14(22-4)13(21-3)6-10(12)5-11-8-19-16(18)20-15(11)17/h6-9H,5H2,1-4H3,(H4,17,18,19,20) |
| InChIKey | PYNPWUIBJMVRIG-UHFFFAOYSA-N |
| SMILES | CC(C)C1=CC(=C(C=C1CC2=CN=C(N=C2N)N)OC)OC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
