For research use only. Not for therapeutic Use.
RNF114 Ligand 1(CAT: I040548) is a novel small-molecule ligand that selectively binds to RNF114, an E3 ubiquitin ligase involved in protein homeostasis and immune regulation. This compound serves as a molecular tool for modulating RNF114 activity and has potential utility in targeted protein degradation strategies, such as PROTAC design. By engaging RNF114, RNF114 Ligand 1 enables the recruitment of target proteins for ubiquitination and proteasomal degradation, offering a platform for the development of next-generation therapeutics. It is particularly useful in studies exploring ubiquitin–proteasome system dynamics, immune signaling, and the design of degrader-based modalities. Suitable for chemical biology and drug discovery research.
| CAS Number | 900137-36-2 |
| Synonyms | 2-chloro-1-[2-(2,5-dimethoxyphenyl)pyrrolidin-1-yl]ethanone |
| Molecular Formula | C14H18ClNO3 |
| Purity | ≥95% |
| IUPAC Name | 2-chloro-1-[2-(2,5-dimethoxyphenyl)pyrrolidin-1-yl]ethanone |
| InChI | InChI=1S/C14H18ClNO3/c1-18-10-5-6-13(19-2)11(8-10)12-4-3-7-16(12)14(17)9-15/h5-6,8,12H,3-4,7,9H2,1-2H3 |
| InChIKey | RZXUCAQMZIQIRL-UHFFFAOYSA-N |
| SMILES | COC1=CC(=C(C=C1)OC)C2CCCN2C(=O)CCl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
