RI(dl)-2 TFA

• CAT Number: I012004
• Molecular Formula: C19H17N3.(1.3)C2HF3O2
• Molecular Weight: 435.59
• Purity: ≥95%
• IUPAC Name: N-ethyl-4-pyrrolo[1,2-a]quinoxalin-4-ylaniline;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C19H17N3.C2HF3O2/c1-2-20-15-11-9-14(10-12-15)19-18-8-5-13-22(18)17-7-4-3-6-16(17)21-19;3-2(4,5)1(6)7/h3-13,20H,2H2,1H3;(H,6,7)
• InChIKey: NIJZNZBFNNPMPH-UHFFFAOYSA-N
• SMILES: CCNC1=CC=C(C=C1)C2=NC3=CC=CC=C3N4C2=CC=C4.C(=O)(C(F)(F)F)O

RI(dl)-2 TFA（Cat No.:I012004）is a synthetic peptide-based inhibitor that targets the interaction between eIF4E and eIF4G, key components of the eukaryotic translation initiation complex. By disrupting this protein-protein interaction, RI(dl)-2 TFA effectively impairs cap-dependent translation, a process often upregulated in cancer cells to support uncontrolled growth and survival. The trifluoroacetate (TFA) salt form enhances peptide stability and solubility for experimental use. RI(dl)-2 TFA is a valuable tool for studying translational control mechanisms and holds potential in cancer research aimed at targeting dysregulated protein synthesis pathways for therapeutic intervention.