Resolvin E1 Sodium Salt

• CAT Number: R059513
• CAS Number: 1309610-43-2
• Molecular Formula: C₂₀H₂₉NaO₅
• Molecular Weight: 372.43
• Purity: ≥95%
• Synonyms: (5S,6Z,8E,10E,12R,14Z,16E,18R)-5,12,18-Trihydroxy-6,8,10,14,16-eicosapentaenoic Acid Sodium Salt
• Storage: -20°C
• IUPAC Name: sodium;(5S,6Z,8E,10E,12R,14Z,16E,18R)-5,12,18-trihydroxyicosa-6,8,10,14,16-pentaenoate
• InChI: InChI=1S/C20H30O5.Na/c1-2-17(21)11-8-5-9-14-18(22)12-6-3-4-7-13-19(23)15-10-16-20(24)25;/h3-9,11-13,17-19,21-23H,2,10,14-16H2,1H3,(H,24,25);/q;+1/p-1/b4-3+,9-5-,11-8+,12-6+,13-7-;/t17-,18+,19-;/m1./s1
• InChIKey: WUXDCPCRUFHVSO-AANQWZQHSA-M
• SMILES: CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)[O-])O)O)O.[Na+]

Resolvin E1 sodium salt（Cat No.:R059513）is a bioactive lipid mediator derived from the omega-3 fatty acid eicosapentaenoic acid (EPA), presented in its stabilized sodium salt form for enhanced solubility and handling. It plays a critical role in actively resolving inflammation without immunosuppression by modulating leukocyte activity, reducing pro-inflammatory cytokine production, and promoting tissue repair. Resolvin E1 binds to specific receptors like ChemR23 and BLT1, influencing immune cell behavior in inflammatory responses. It is widely studied in models of chronic inflammatory diseases, including arthritis, cardiovascular disorders, and neuroinflammation, for its therapeutic potential in pro-resolving pharmacology.