For research use only. Not for therapeutic Use.
RBPJ Inhibitor-1（Cat No.:I044668）is a small molecule that selectively targets the transcription factor RBPJ, a core component of the canonical Notch signaling pathway. By disrupting the RBPJ-DNA interaction, it effectively blocks Notch-dependent gene transcription, making it a valuable tool in studying Notch-mediated processes. This inhibitor is particularly relevant in cancer research, where aberrant Notch signaling is implicated in tumor progression and maintenance of cancer stem cells. RBPJ Inhibitor-1 is a useful candidate for validating therapeutic approaches aimed at modulating Notch activity in disease models.
| CAS Number | 2682114-39-0 |
| Synonyms | 2-(2-fluorophenoxy)-4-(2-methylpyrazol-3-yl)benzamide |
| Molecular Formula | C17H14FN3O2 |
| Purity | ≥95% |
| IUPAC Name | 2-(2-fluorophenoxy)-4-(2-methylpyrazol-3-yl)benzamide |
| InChI | InChI=1S/C17H14FN3O2/c1-21-14(8-9-20-21)11-6-7-12(17(19)22)16(10-11)23-15-5-3-2-4-13(15)18/h2-10H,1H3,(H2,19,22) |
| InChIKey | MFSSHRCJKRDIOL-UHFFFAOYSA-N |
| SMILES | CN1C(=CC=N1)C2=CC(=C(C=C2)C(=O)N)OC3=CC=CC=C3F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
