RAGE 229

• CAT Number: I043379
• CAS Number: 2143072-85-7
• Molecular Formula: C23H22N4O2
• Molecular Weight: 386.45
• Purity: ≥95%
• Synonyms: N-[4-[7-cyano-4-(morpholin-4-ylmethyl)quinolin-2-yl]phenyl]acetamide
• InChI: InChI=1S/C23H22N4O2/c1-16(28)25-20-5-3-18(4-6-20)22-13-19(15-27-8-10-29-11-9-27)21-7-2-17(14-24)12-23(21)26-22/h2-7,12-13H,8-11,15H2,1H3,(H,25,28)
• InChIKey: VDYYVNHJRNDKDO-UHFFFAOYSA-N
• SMILES: CC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=CC(=C3)C#N)C(=C2)CN4CCOCC4

RAGE 229（Cat No.:I043379）is a selective small molecule inhibitor targeting the receptor for advanced glycation end-products (RAGE), a protein involved in chronic inflammation and the progression of various diseases. RAGE is implicated in conditions such as diabetes, cardiovascular disease, Alzheimer’s disease, and cancer, where its activation promotes inflammatory responses and tissue damage. By inhibiting RAGE, RAGE 229 aims to block these pathogenic processes, reducing inflammation and preventing tissue injury. This compound is being studied for its potential to treat diseases associated with RAGE overactivation, offering a targeted approach to modulate inflammation and improve disease outcomes.