RAD51-IN-5

• CAT Number: I043715
• CAS Number: 2690367-19-0
• Molecular Formula: C26H38N4O5S2
• Molecular Weight: 550.73
• Purity: ≥95%
• Synonyms: propan-2-yl N-[4-[2-[4-(propan-2-yloxycarbonylamino)cyclohexyl]-1,3-thiazol-5-yl]-3-(propan-2-ylsulfonimidoyl)phenyl]carbamate
• InChI: InChI=1S/C26H38N4O5S2/c1-15(2)34-25(31)29-19-9-7-18(8-10-19)24-28-14-22(36-24)21-12-11-20(30-26(32)35-16(3)4)13-23(21)37(27,33)17(5)6/h11-19,27H,7-10H2,1-6H3,(H,29,31)(H,30,32)
• InChIKey: IFAJQXQNZPNAHT-UHFFFAOYSA-N
• SMILES: CC(C)OC(=O)NC1CCC(CC1)C2=NC=C(S2)C3=C(C=C(C=C3)NC(=O)OC(C)C)S(=N)(=O)C(C)C

RAD51-IN-5（Cat No.:I043715）is a selective inhibitor of RAD51, a key protein involved in homologous recombination repair of DNA double-strand breaks. RAD51 plays an essential role in maintaining genome stability and repairing DNA damage, which is critical for cell survival, especially during cell division. By inhibiting RAD51, RAD51-IN-5 can disrupt DNA repair processes, making it a promising compound for enhancing the effects of DNA-damaging therapies, such as chemotherapy and radiation, in cancer treatment. It is being investigated for its potential to sensitize cancer cells to DNA-damaging agents, offering a targeted approach to cancer therapy.