(Rac)-Upacicalcet

• CAT Number: I043740
• CAS Number: 2649575-19-7
• Molecular Formula: C11H14ClN3O6S
• Molecular Weight: 351.76
• Purity: ≥95%
• Synonyms: 2-amino-3-[(3-chloro-2-methyl-5-sulfophenyl)carbamoylamino]propanoic acid
• InChI: InChI=1S/C11H14ClN3O6S/c1-5-7(12)2-6(22(19,20)21)3-9(5)15-11(18)14-4-8(13)10(16)17/h2-3,8H,4,13H2,1H3,(H,16,17)(H2,14,15,18)(H,19,20,21)
• InChIKey: LHEYGVSDVBEYQF-UHFFFAOYSA-N
• SMILES: CC1=C(C=C(C=C1Cl)S(=O)(=O)O)NC(=O)NCC(C(=O)O)N

(Rac)-Upacicalcet（Cat No.:I043740）is a synthetic compound and a selective calcium-sensing receptor (CaSR) agonist used in the treatment of secondary hyperparathyroidism, particularly in patients with chronic kidney disease. By binding to and activating the CaSR, (Rac)-Upacicalcet helps to reduce parathyroid hormone (PTH) secretion, thereby normalizing calcium and phosphate balance in the body. This compound aims to manage the mineral metabolism disturbances associated with kidney disease. (Rac)-Upacicalcet holds promise as an effective therapeutic agent for improving bone and mineral health in patients undergoing dialysis or those with impaired renal function.