(Rac)-Taltobulin intermediate-1

• CAT Number: I040502
• CAS Number: 676487-35-7
• Molecular Formula: C17H25NO4
• Molecular Weight: 307.38
• Purity: ≥95%
• Synonyms: 3-methyl-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-phenylbutanoic acid
• InChI: InChI=1S/C17H25NO4/c1-16(2,3)22-15(21)18(6)13(14(19)20)17(4,5)12-10-8-7-9-11-12/h7-11,13H,1-6H3,(H,19,20)
• InChIKey: ZWQAFCGLXUTMKH-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N(C)C(C(=O)O)C(C)(C)C1=CC=CC=C1

(Rac)-Taltobulin Intermediate-1(CAT: I040502) is a racemic synthetic intermediate used in the preparation of Taltobulin (HY-15584), a highly potent microtubule-targeting agent widely employed as a cytotoxic payload in antibody-drug conjugates (ADCs). This intermediate plays a critical role in constructing the core structure of Taltobulin, which functions by disrupting tubulin polymerization, inducing mitotic arrest, and promoting apoptosis in rapidly dividing cancer cells. As a racemic mixture, it offers versatility for downstream resolution or further modification in medicinal chemistry workflows. Supplied in high purity, (Rac)-Taltobulin Intermediate-1 is ideal for ADC payload synthesis and cancer therapeutic development in preclinical research settings.