(Rac)-PF-998425（Cat No.:I045211）is a racemic small-molecule inhibitor targeting tropomyosin receptor kinase A (TrkA), a high-affinity receptor for nerve growth factor (NGF) involved in pain signaling, neuronal survival, and differentiation. By blocking TrkA kinase activity, (Rac)-PF-998425 suppresses NGF-mediated downstream pathways, reducing nociceptive signaling and inflammation-associated pain. It is a valuable research tool for studying neurotrophin signaling, pain mechanisms, and TrkA-dependent neuronal processes. (Rac)-PF-998425 holds therapeutic potential for treating chronic pain, inflammatory disorders, and neurodegenerative diseases where aberrant TrkA activation contributes to pathology.