(Rac)-NNC 55-0396

• CAT Number: I040451
• CAS Number: 2517420-92-5
• Molecular Formula: C30H40Cl2FN3O2
• Molecular Weight: 564.56
• Purity: ≥95%
• Synonyms: [2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] cyclopropanecarboxylate;dihydrochloride
• InChI: InChI=1S/C30H38FN3O2.2ClH/c1-20(2)28-24-13-12-23(31)19-22(24)14-15-30(28,36-29(35)21-10-11-21)16-18-34(3)17-6-9-27-32-25-7-4-5-8-26(25)33-27;;/h4-5,7-8,12-13,19-21,28H,6,9-11,14-18H2,1-3H3,(H,32,33);2*1H
• InChIKey: BCCQNBXHUMKLFW-UHFFFAOYSA-N
• SMILES: CC(C)C1C2=C(CCC1(CCN(C)CCCC3=NC4=CC=CC=C4N3)OC(=O)C5CC5)C=C(C=C2)F.Cl.Cl

(Rac)-NNC 55-0396(CAT: I040451) is a racemic form of a selective T-type calcium channel blocker, widely used in neuroscience and cardiovascular research. It exhibits high specificity for low-voltage-activated T-type calcium channels (Cav3.x), which play a pivotal role in neuronal excitability, pacemaker activity, and pain transmission. Unlike other calcium channel inhibitors, (Rac)-NNC 55-0396 offers improved selectivity and reduced activity on L-type channels, minimizing off-target effects. This compound is valuable for studying the physiological and pathological roles of T-type channels in epilepsy, neuropathic pain, and cardiac arrhythmias. It serves as a powerful pharmacological tool in electrophysiological assays and ion channel-targeted drug development.