(Rac)-Indoximod

• CAT Number: I045304
• CAS Number: 26988-72-7
• Molecular Formula: C12H14N2O2
• Molecular Weight: 218.25
• Purity: ≥95%
• IUPAC Name: 2-amino-3-(1-methylindol-3-yl)propanoic acid
• InChI: InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)
• InChIKey: ZADWXFSZEAPBJS-UHFFFAOYSA-N
• SMILES: CN1C=C(C2=CC=CC=C21)CC(C(=O)O)N

(Rac)-Indoximod（Cat No.:I045304）is the racemic form of an indoleamine 2,3-dioxygenase (IDO) pathway inhibitor used in cancer immunotherapy research. By modulating tryptophan metabolism and blocking the immunosuppressive effects of kynurenine accumulation, it helps restore T-cell activation and enhance antitumor immune responses. The racemic mixture contains both enantiomers, enabling comprehensive evaluation of biological activity and pharmacokinetics. (Rac)-Indoximod has been studied in combination with immune checkpoint inhibitors, chemotherapy, and vaccines to improve therapeutic efficacy. It serves as a valuable tool for investigating immune regulation and developing novel strategies to overcome tumor-induced immune suppression.