For research use only. Not for therapeutic Use.
(Rac)-EC5026（Cat No.:I044516）is a racemic small-molecule inhibitor of soluble epoxide hydrolase (sEH), an enzyme that metabolizes epoxyeicosatrienoic acids (EETs) into less active diols. By inhibiting sEH, (Rac)-EC5026 enhances EET levels, promoting their beneficial effects such as anti-inflammatory, vasodilatory, and analgesic actions. It is primarily investigated for the treatment of chronic pain, inflammation, and cardiovascular disorders. The racemic mixture contains both enantiomers of EC5026, offering broad pharmacological activity in preclinical models. (Rac)-EC5026 is a promising candidate in drug development targeting lipid signaling pathways for non-opioid pain and inflammation management.
| CAS Number | 1809885-55-9 |
| Synonyms | 1-[3-fluoro-4-(trifluoromethoxy)phenyl]-3-[1-(2-methylbutanoyl)piperidin-4-yl]urea |
| Molecular Formula | C18H23F4N3O3 |
| Purity | ≥95% |
| IUPAC Name | 1-[3-fluoro-4-(trifluoromethoxy)phenyl]-3-[1-(2-methylbutanoyl)piperidin-4-yl]urea |
| InChI | InChI=1S/C18H23F4N3O3/c1-3-11(2)16(26)25-8-6-12(7-9-25)23-17(27)24-13-4-5-15(14(19)10-13)28-18(20,21)22/h4-5,10-12H,3,6-9H2,1-2H3,(H2,23,24,27) |
| InChIKey | LHRXHTKENPCGSZ-UHFFFAOYSA-N |
| SMILES | CCC(C)C(=O)N1CCC(CC1)NC(=O)NC2=CC(=C(C=C2)OC(F)(F)F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
