(Rac)-BIO8898

• CAT Number: I044117
• CAS Number: 402564-79-8
• Molecular Formula: C53H64N8O6
• Molecular Weight: 909.13
• Purity: ≥95%
• Synonyms: 2-cyclohexyl-2-[[4-[2-[(3-phenylphenyl)methylcarbamoyl]-6-[2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl]pyridin-4-yl]-6-[2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl]pyridine-2-carbonyl]amino]acetic acid
• InChI: InChI=1S/C53H64N8O6/c62-49(54-33-36-14-11-19-39(28-36)37-15-3-1-4-16-37)44-29-40(31-46(55-44)51(64)60-26-12-20-42(60)34-58-22-7-8-23-58)41-30-45(50(63)57-48(53(66)67)38-17-5-2-6-18-38)56-47(32-41)52(65)61-27-13-21-43(61)35-59-24-9-10-25-59/h1,3-4,11,14-16,19,28-32,38,42-43,48H,2,5-10,12-13,17-18,20-27,33-35H2,(H,54,62)(H,57,63)(H,66,67)
• InChIKey: WJYLSDLKLWXYML-UHFFFAOYSA-N
• SMILES: C1CCC(CC1)C(C(=O)O)NC(=O)C2=NC(=CC(=C2)C3=CC(=NC(=C3)C(=O)N4CCCC4CN5CCCC5)C(=O)NCC6=CC(=CC=C6)C7=CC=CC=C7)C(=O)N8CCCC8CN9CCCC9

(Rac)-BIO8898（Cat No.:I044117）is a small-molecule antagonist that selectively targets CD40–CD40L interactions, a key co-stimulatory pathway involved in immune regulation and inflammation. By inhibiting this protein–protein interaction, (Rac)-BIO8898 modulates immune cell activation, making it a valuable tool in immunology research. It has shown potential in models of autoimmune diseases, transplant rejection, and chronic inflammation by reducing T-cell activation and cytokine production. As a racemic mixture, it provides insights into stereochemical aspects of drug activity. (Rac)-BIO8898 supports therapeutic exploration of immune-modulating strategies with reduced systemic immune suppression.