(R)-Rabeprazole Sodium Salt

• CAT Number: R048154
• CAS Number: 171440-18-9
• Molecular Formula: C₁₈H₂₀N₃NaO₃S
• Molecular Weight: 381.42
• Purity: ≥95%
• Synonyms: 2-[(R)-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole Sodium Salt; R-(+)-Rabeprazole Sodium Salt
• Storage: Store at -20°C
• IUPAC Name: sodium;2-[(R)-[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl]benzimidazol-1-ide
• InChI: InChI=1S/C18H20N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3;/q-1;+1/t25-;/m1./s1
• InChIKey: KRCQSTCYZUOBHN-VQIWEWKSSA-N
• SMILES: CC1=C(C=CN=C1C[S@@](=O)C2=NC3=CC=CC=C3[N-]2)OCCCOC.[Na+]

(R)-Rabeprazole sodium salt(CAT: R048154) is the enantiomerically pure sodium salt form of rabeprazole, a proton pump inhibitor (PPI) used to suppress gastric acid secretion. It appears as a white to off-white crystalline powder, freely soluble in water and methanol. Acting by irreversibly inhibiting the H⁺/K⁺-ATPase enzyme in gastric parietal cells, (R)-rabeprazole reduces gastric acidity, aiding in the treatment of gastroesophageal reflux disease (GERD), peptic ulcers, and other acid-related disorders. The (R)-enantiomer may offer pharmacokinetic advantages over the racemic mixture, including improved metabolic stability