(R)-Pregabalin

• CAT Number: R052996
• CAS Number: 148553-51-9
• Molecular Formula: C8H17NO2
• Molecular Weight: 159.23
• Purity: ≥95%
• Synonyms: (3R)-3-(Aminomethyl)-5-methylhexanoic acid; (R)-3-(Aminomethyl)-5-methylhexanoic acid; PD 144550; ent-Pregabalin
• Storage: -20°C
• IUPAC Name: (3R)-3-(aminomethyl)-5-methylhexanoic acid
• InChI: InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m1/s1
• InChIKey: AYXYPKUFHZROOJ-SSDOTTSWSA-N
• SMILES: CC(C)CC(CC(=O)O)CN

(R)-Pregabalin (Cat No.: R052996) is the enantiomer of the therapeutic compound pregabalin, with the molecular formula C₈H₁₇NO₂. Structurally related to the neurotransmitter GABA, it features an (R)-configured isobutyl side chain attached to a substituted propionic acid backbone. While the (S)-enantiomer is the pharmacologically active form approved for treating neuropathic pain, epilepsy, and anxiety, (R)-pregabalin is significantly less active at α2δ subunits of voltage-gated calcium channels. It is primarily studied in research settings to explore stereoselectivity and the enantiomer-specific effects of pregabalin.