(R)-MLN-4760

• CAT Number: I045051
• CAS Number: 305335-29-9
• Molecular Formula: C19H23Cl2N3O4
• Molecular Weight: 428.31
• Purity: ≥95%
• Synonyms: (2R)-2-[[(1S)-1-carboxy-2-[3-[(3,5-dichlorophenyl)methyl]imidazol-4-yl]ethyl]amino]-4-methylpentanoic acid
• InChI: InChI=1S/C19H23Cl2N3O4/c1-11(2)3-16(18(25)26)23-17(19(27)28)7-15-8-22-10-24(15)9-12-4-13(20)6-14(21)5-12/h4-6,8,10-11,16-17,23H,3,7,9H2,1-2H3,(H,25,26)(H,27,28)/t16-,17+/m1/s1
• InChIKey: NTCCRGGIJNDEAB-SJORKVTESA-N
• SMILES: CC(C)C[C@H](C(=O)O)N[C@@H](CC1=CN=CN1CC2=CC(=CC(=C2)Cl)Cl)C(=O)O

(R)-MLN-4760（Cat No.:I045051）is a highly selective and potent inhibitor of angiotensin-converting enzyme 2 (ACE2), a key regulator in the renin-angiotensin system (RAS). By binding to ACE2, (R)-MLN-4760 blocks the conversion of angiotensin II to angiotensin-(1–7), thereby modulating blood pressure, fluid balance, and inflammatory responses. This compound is widely used in cardiovascular and renal disease research, as well as in studies exploring ACE2’s role in viral entry mechanisms, including SARS-CoV-2. (R)-MLN-4760 serves as a valuable tool in elucidating ACE2-associated pathways. For laboratory research use only.