For research use only. Not for therapeutic Use.
(R)-Mirtazapine(CAT: R045054) ((R)-Org3770) is the R(−)-enantiomer of Mirtazapine, exhibiting distinct pharmacological properties compared to the racemate. It functions as a selective 5-HT3 receptor antagonist, contributing to its antinociceptive effects in animal models of acute thermal nociception. Unlike the parent compound primarily known for antidepressant activity, (R)-Mirtazapine demonstrates potential in modulating pain perception through serotonergic pathways. It is predominantly metabolized by CYP3A4, highlighting its defined metabolic profile. With its receptor selectivity and preclinical analgesic effects, (R)-Mirtazapine serves as a useful research tool for studying serotonin-mediated signaling, nociception, and the enantioselective pharmacology of Mirtazapine derivatives.
| CAS Number | 61364-37-2 |
| Synonyms | (7R)-5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(15),8,10,12,16,18-hexaene |
| Molecular Formula | C17H19N3 |
| Purity | ≥95% |
| IUPAC Name | (7R)-5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(15),8,10,12,16,18-hexaene |
| InChI | InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3/t16-/m0/s1 |
| InChIKey | RONZAEMNMFQXRA-INIZCTEOSA-N |
| SMILES | CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
