(R)-CPP

• CAT Number: M112894
• CAS Number: 126453-07-4
• Molecular Formula: C8H17N2O5P
• Molecular Weight: 252.20
• Purity: ≥95%
• Synonyms: (2R)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid
• InChI: InChI=1S/C8H17N2O5P/c11-8(12)7-6-10(4-2-9-7)3-1-5-16(13,14)15/h7,9H,1-6H2,(H,11,12)(H2,13,14,15)/t7-/m1/s1
• InChIKey: CUVGUPIVTLGRGI-SSDOTTSWSA-N
• SMILES: C1CN(C[C@@H](N1)C(=O)O)CCCP(=O)(O)O

(R)-CPP (Cat No.:M112894) is a potent, selective antagonist of NMDA (N-methyl-D-aspartate) receptors, specifically targeting the glutamate-binding site. It is widely used in neuroscience research to investigate synaptic plasticity, learning, memory, and excitotoxicity. By blocking NMDA receptor activity, (R)-CPP helps elucidate mechanisms underlying neurodegenerative diseases, epilepsy, and cognitive dysfunction. Its high affinity and specificity make it a valuable tool in in vivo and in vitro studies examining glutamatergic neurotransmission. (R)-CPP is particularly useful in assessing the role of NMDA-dependent long-term potentiation (LTP) and long-term depression (LTD) in brain function.