(R)-Benzyl 2-cyclopropyl-2-hydroxyacetate

• CAT Number: I040504
• CAS Number: 2414393-47-6
• Molecular Formula: C12H14O3
• Molecular Weight: 206.24
• Purity: ≥95%
• Synonyms: benzyl (2R)-2-cyclopropyl-2-hydroxyacetate
• InChI: InChI=1S/C12H14O3/c13-11(10-6-7-10)12(14)15-8-9-4-2-1-3-5-9/h1-5,10-11,13H,6-8H2/t11-/m1/s1
• InChIKey: HBEZCBDGJMYNGS-LLVKDONJSA-N
• SMILES: C1CC1C(C(=O)OCC2=CC=CC=C2)O

(R)-Benzyl 2-cyclopropyl-2-hydroxyacetate(CAT: I040504) is a chiral building block featuring a cyclopropyl-substituted α-hydroxy ester with a benzyl protecting group. This enantiomerically enriched intermediate is particularly valuable in the synthesis of pyrrolidine-based compounds, which are frequently incorporated into linker or payload structures in antibody-drug conjugate (ADC) development. Its stereochemistry and functional groups enable precise control in downstream transformations, supporting the assembly of structurally defined and biologically active molecules. (R)-Benzyl 2-cyclopropyl-2-hydroxyacetate is ideal for use in asymmetric synthesis, medicinal chemistry, and ADC linker design. Supplied in high purity, it facilitates high-fidelity construction of complex chiral frameworks for targeted cancer therapeutics.