R-3-(N-Benzyloxycarbonylpyrrolidin-2-ylcarbonyl)-5-bromo-1H-indole

• CAT Number: R005287
• CAS Number: 143322-56-9
• Molecular Formula: C21H19BrN2O3
• Molecular Weight: 427.29
• Purity: ≥95%
• Synonyms: (2R)-2-[(5-Bromo-1H-indol-3-yl)carbonyl]-1-pyrrolidinecarboxylic Acid Phenylmethyl Ester
• Storage: Store at -20°C
• IUPAC Name: benzyl (2R)-2-(5-bromo-1H-indole-3-carbonyl)pyrrolidine-1-carboxylate
• InChI: InChI=1S/C21H19BrN2O3/c22-15-8-9-18-16(11-15)17(12-23-18)20(25)19-7-4-10-24(19)21(26)27-13-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,19,23H,4,7,10,13H2/t19-/m1/s1
• InChIKey: CWHKVBJSRGJFFN-LJQANCHMSA-N
• SMILES: C1CC(N(C1)C(=O)OCC2=CC=CC=C2)C(=O)C3=CNC4=C3C=C(C=C4)Br

R-3-(N-Benzyloxycarbonylpyrrolidin-2-ylcarbonyl)-5-bromo-1H-indole (Cat No.: R005287) is a complex chiral molecule featuring an indole core substituted with a bromo group at the 5-position and a pyrrolidinylcarbonyl side chain protected by a benzyloxycarbonyl (Cbz) group. This compound is used as a synthetic intermediate in the development of bioactive molecules, particularly in peptide-based or indole-containing drug candidates. The presence of both a stereocenter and multiple functional groups makes it suitable for structure-activity relationship (SAR) studies in medicinal chemistry, especially targeting neurological or oncological pathways.