(R)-2,2'-Bis[bis(3,5-trifluoromethylphenyl)phosphino]-4,4',6,6'-tetramethoxy)-1,1'-biphenyl

• CAT Number: L002537
• CAS Number: 1365531-84-5
• Molecular Formula: C48H28F24O4P2
• Molecular Weight: 1186.61
• Purity: ≥95%
• IUPAC Name: [2-[2-bis[3,5-bis(trifluoromethyl)phenyl]phosphanyl-4,6-dimethoxyphenyl]-3,5-dimethoxyphenyl]-bis[3,5-bis(trifluoromethyl)phenyl]phosphane
• InChI: InChI=1S/C48H28F24O4P2/c1-73-29-17-35(75-3)39(37(19-29)77(31-9-21(41(49,50)51)5-22(10-31)42(52,53)54)32-11-23(43(55,56)57)6-24(12-32)44(58,59)60)40-36(76-4)18-30(74-2)20-38(40)78(33-13-25(45(61,62)63)7-26(14-33)46(64,65)66)34-15-27(47(67,68)69)8-28(16-34)48(70,71)72/h5-20H,1-4H3
• InChIKey: JDKXXRZDVSJSNQ-UHFFFAOYSA-N
• SMILES: COC1=CC(=C(C(=C1)P(C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C4=C(C=C(C=C4P(C5=CC(=CC(=C5)C(F)(F)F)C(F)(F)F)C6=CC(=CC(=C6)C(F)(F)F)C(F)(F)F)OC)OC)OC

(R)-2,2′-Bis[bis(3,5-trifluoromethylphenyl)phosphino]-4,4′,6,6′-tetramethoxy-1,1′-biphenyl(CAT: L002537) is a chiral, electron-rich diphosphine ligand designed for enantioselective catalysis. Its bulky trifluoromethyl-substituted aryl groups and tetramethoxy biphenyl backbone offer excellent steric and electronic control, making it highly effective in asymmetric hydrogenation, C–C bond formation, and transition metal-catalyzed reactions. This ligand is widely employed in both academic and industrial research for the synthesis of chiral pharmaceuticals and fine chemicals. Its rigid, atropisomeric structure ensures high enantioselectivity, while the fluorinated aryl substituents enhance catalyst stability and activity. Ideal for developing high-performance chiral catalysts, it is a key tool in stereoselective synthesis and green chemistry applications.