Quetiapine Fumarate

• CAT Number: A001042
• CAS Number: 111974-72-2
• Molecular Formula: C21H25N3O2S • 1/2C4H4O4
• Molecular Weight: 441.50
• Purity: ≥95%
• Synonyms: ICI-204636
• Target: Neuronal Signaling
• Solubility: >11mg/mL in DMSO
• Storage: 3 years -20C powder
• IUPAC Name: 2-[2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethoxy]ethanol;(E)-but-2-enedioic acid
• InChI: InChI=1S/2C21H25N3O2S.C4H4O4/c2*25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h2*1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;;2-1+
• InChIKey: ZTHJULTYCAQOIJ-WXXKFALUSA-N
• SMILES: C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42.C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42.C(=C/C(=O)O)\C(=O)O

Quetiapine Fumarate（Cat No.:A001042）is an atypical antipsychotic medication with the molecular formula C21H25N3O5·C4H4O4, commonly used to treat schizophrenia, bipolar disorder, and major depressive disorder. It functions primarily by antagonizing dopamine D2 and serotonin 5-HT2A receptors, helping to balance neurotransmitter activity in the brain. The fumarate salt form enhances its stability and bioavailability. Quetiapine is available in immediate and extended-release formulations and is usually taken orally. Common side effects include drowsiness, dry mouth, dizziness, and weight gain. It must be prescribed and monitored carefully due to potential metabolic and neurological risks.