For research use only. Not for therapeutic Use.
PTUPB（Cat No.:I015546）is a dual inhibitor targeting both soluble epoxide hydrolase (sEH) and cyclooxygenase-2 (COX-2), designed to provide anti-inflammatory and analgesic benefits. By simultaneously blocking sEH and COX-2 pathways, PTUPB enhances the bioavailability of epoxy-fatty acids while reducing pro-inflammatory prostaglandins, resulting in synergistic effects against pain, inflammation, and tumor progression. Preclinical studies suggest its potential in cancer therapy, neuropathic pain, and inflammatory diseases. Its dual-action mechanism makes PTUPB a valuable research tool for exploring novel therapeutic strategies in oncology, immunology, and metabolic disease research.
| CAS Number | 1287761-01-6 |
| Synonyms | 1-[3-[5-phenyl-1-(4-sulfamoylphenyl)pyrazol-3-yl]propyl]-3-[4-(trifluoromethyl)phenyl]urea |
| Molecular Formula | C26H24F3N5O3S |
| Purity | ≥95% |
| IUPAC Name | 1-[3-[5-phenyl-1-(4-sulfamoylphenyl)pyrazol-3-yl]propyl]-3-[4-(trifluoromethyl)phenyl]urea |
| InChI | InChI=1S/C26H24F3N5O3S/c27-26(28,29)19-8-10-20(11-9-19)32-25(35)31-16-4-7-21-17-24(18-5-2-1-3-6-18)34(33-21)22-12-14-23(15-13-22)38(30,36)37/h1-3,5-6,8-15,17H,4,7,16H2,(H2,30,36,37)(H2,31,32,35) |
| InChIKey | CSEPEVFNTFMBAE-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)CCCNC(=O)NC4=CC=C(C=C4)C(F)(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
