Protease-Activated Receptor-1, PAR-1 Agonist TFA

• CAT Number: I044270
• Molecular Formula: C37H59F3N10O11
• Molecular Weight: 876.92
• Purity: ≥95%
• Synonyms: (2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-oxobutanoic acid;2,2,2-trifluoroacetic acid

Protease-Activated Receptor-1 (PAR-1) Agonist TFA（Cat No.:I044270）is a synthetic peptide that mimics the tethered ligand sequence exposed upon thrombin-mediated cleavage of PAR-1, a G-protein-coupled receptor. This agonist activates PAR-1 signaling pathways involved in platelet aggregation, vascular function, inflammation, and cell proliferation. It is widely used in research to study thrombin signaling without proteolytic activity. The TFA (trifluoroacetate) form refers to the peptide being stabilized as a trifluoroacetate salt, commonly used for peptide preservation. This reagent is essential in cardiovascular, cancer, and neurological disease research models.