Propionylpromazine hydrochloride

• CAT Number: R000384
• CAS Number: 7681-67-6
• Molecular Formula: C20H25ClN2OS
• Molecular Weight: 376.94
• Purity: ≥95%
• Synonyms: 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one;hydrochloride
• InChI: InChI=1S/C20H24N2OS.ClH/c1-4-18(23)15-10-11-20-17(14-15)22(13-7-12-21(2)3)16-8-5-6-9-19(16)24-20;/h5-6,8-11,14H,4,7,12-13H2,1-3H3;1H
• InChIKey: ZFWVWZODBGTOIL-UHFFFAOYSA-N
• SMILES: CCC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN(C)C.Cl

Propionylpromazine hydrochloride（Cat No.:R000384）is a phenothiazine derivative with neuroleptic and sedative properties, structurally related to chlorpromazine. Acting primarily as a dopamine receptor antagonist, it modulates dopaminergic neurotransmission while also interacting with histamine and adrenergic receptors, contributing to its tranquilizing effects. It has been investigated for its potential in psychiatric and neurological research, particularly in studying antipsychotic mechanisms and sedation pathways. Researchers use Propionylpromazine hydrochloride to explore dopaminergic signaling, receptor pharmacology, and therapeutic strategies targeting psychosis, agitation, and related central nervous system disorders.