Propargyl-PEG9-amine

• CAT Number: I014647
• CAS Number: 2093153-98-9
• Molecular Formula: C21H41NO9
• Molecular Weight: 451.55
• Purity: ≥95%
• Synonyms: 2-[2-[2-[2-[2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
• InChI: InChI=1S/C21H41NO9/c1-2-4-23-6-8-25-10-12-27-14-16-29-18-20-31-21-19-30-17-15-28-13-11-26-9-7-24-5-3-22/h1H,3-22H2
• InChIKey: HWOGUEROMVALKI-UHFFFAOYSA-N
• SMILES: C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCN

Propargyl-PEG9-amine(CAT: I014647) is a heterobifunctional polyethylene glycol (PEG) linker featuring a terminal propargyl (alkyne) group for copper-catalyzed or strain-promoted azide–alkyne cycloaddition (“click chemistry”) and a primary amine for conjugation with carboxylic acids, activated esters, or other electrophiles. The PEG9 spacer imparts excellent hydrophilicity, flexibility, and aqueous solubility, while minimizing steric hindrance during coupling reactions. This versatile dual-functional linker enables efficient, orthogonal modifications for the synthesis of bioconjugates, PROTACs, antibody–drug conjugates, surface modifications, and nanomaterials. Propargyl-PEG9-amine is an ideal building block for applications requiring long, hydrophilic, and flexible linkers with reliable reactivity in both biological and materials science research.