For research use only. Not for therapeutic Use.
Propargyl-PEG6-N3 (Cat No.: I014636) is a bifunctional, click chemistry–ready linker featuring a terminal propargyl group and an azide moiety connected by a PEG6 spacer (six ethylene glycol units). The propargyl and azide groups enable copper-catalyzed azide–alkyne cycloaddition (CuAAC) or strain-promoted click reactions, allowing versatile bioconjugation. The PEG6 linker improves solubility, flexibility, and reduces steric hindrance, making it suitable for linking biomolecules, drugs, or probes. Propargyl-PEG6-N3 is widely used in chemical biology, drug discovery, and materials science for constructing multifunctional molecules and targeted delivery systems.
CAS Number | 1198080-03-3 |
Synonyms | 3-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]prop-1-yne |
Molecular Formula | C15H27N3O6 |
Purity | ≥95% |
InChI | InChI=1S/C15H27N3O6/c1-2-4-19-6-8-21-10-12-23-14-15-24-13-11-22-9-7-20-5-3-17-18-16/h1H,3-15H2 |
InChIKey | PZHVNVDINOLKDX-UHFFFAOYSA-N |
SMILES | C#CCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] |
Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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