(Pro3) GIP, human TFA

• CAT Number: I040200
• Molecular Formula: C226H338N60O64S.xC2HF3O2
• Molecular Weight: 4951.53 (free base)
• Purity: ≥95%

(Pro³) GIP, human TFA(CAT: I040200) is a potent and selective full agonist of the human GIP receptor (hGIPR), engineered for enhanced efficacy, stability, and receptor specificity. Incorporation of a proline at position 3 significantly improves its resistance to enzymatic degradation while maintaining strong functional activity. It binds hGIPR with high affinity (Kᵢ/K_d = 0.90 nM), making it a valuable tool for studying GIPR-mediated signaling. (Pro³) GIP, human TFA is particularly useful in obesity and type 2 diabetes research, where GIP plays a crucial role in glucose homeostasis, insulin secretion, and energy balance.