For research use only. Not for therapeutic Use.
PRMT5-IN-30(CAT: I035027) is a potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5), an epigenetic enzyme implicated in gene regulation, RNA processing, and tumor progression. This small-molecule compound exhibits strong binding affinity and specificity for PRMT5, making it a valuable research tool for studying methylation-dependent cellular mechanisms and oncogenic pathways. PRMT5-IN-30 is widely used in preclinical cancer models to evaluate the therapeutic potential of PRMT5 inhibition, particularly in hematological malignancies and solid tumors. Its well-defined pharmacological profile supports applications in epigenetic drug discovery, mechanism-of-action studies, and the exploration of PRMT5’s role in transcriptional repression and cell proliferation.
| CAS Number | 330951-01-4 |
| Synonyms | methyl 2-[[2-[(6-methoxy-1H-benzimidazol-2-yl)sulfanyl]acetyl]amino]benzoate |
| Molecular Formula | C18H17N3O4S |
| Purity | ≥95% |
| IUPAC Name | methyl 2-[[2-[(6-methoxy-1H-benzimidazol-2-yl)sulfanyl]acetyl]amino]benzoate |
| InChI | InChI=1S/C18H17N3O4S/c1-24-11-7-8-14-15(9-11)21-18(20-14)26-10-16(22)19-13-6-4-3-5-12(13)17(23)25-2/h3-9H,10H2,1-2H3,(H,19,22)(H,20,21) |
| InChIKey | GZBULYAKSCNNPA-UHFFFAOYSA-N |
| SMILES | COC1=CC2=C(C=C1)N=C(N2)SCC(=O)NC3=CC=CC=C3C(=O)OC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
