Pritelivir mesylate

• CAT Number: I014580
• CAS Number: 1428333-96-3
• Molecular Formula: C19H22N4O6S3
• Molecular Weight: 498.60
• Purity: ≥95%
• Synonyms: methanesulfonic acid;N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2-(4-pyridin-2-ylphenyl)acetamide
• InChI: InChI=1S/C18H18N4O3S2.CH4O3S/c1-12-17(27(19,24)25)26-18(21-12)22(2)16(23)11-13-6-8-14(9-7-13)15-5-3-4-10-20-15;1-5(2,3)4/h3-10H,11H2,1-2H3,(H2,19,24,25);1H3,(H,2,3,4)
• InChIKey: PPAJHCGEURRDOG-UHFFFAOYSA-N
• SMILES: CC1=C(SC(=N1)N(C)C(=O)CC2=CC=C(C=C2)C3=CC=CC=N3)S(=O)(=O)N.CS(=O)(=O)O

Pritelivir mesylate(CAT: I014580) is an orally active, first-in-class helicase–primase inhibitor that targets herpes simplex virus (HSV) replication. Unlike traditional nucleoside analogs, Pritelivir disrupts viral DNA unwinding and priming, effectively inhibiting HSV-1 and HSV-2 proliferation. It exhibits strong antiviral activity in vitro and in vivo, including against acyclovir-resistant strains. The mesylate salt form improves solubility and bioavailability, making it suitable for both experimental and therapeutic research. Pritelivir mesylate has shown promise in clinical evaluation for recurrent genital herpes and is a valuable tool for virology research, antiviral drug development, and studies of herpesvirus pathogenesis.