For research use only. Not for therapeutic Use.
Poricoic Acid AM（Cat No.:I044810）is a triterpenoid compound isolated from Poria cocos, a traditional medicinal fungus used in East Asia. Known for its potent anti-inflammatory and anti-fibrotic properties, Poricoic Acid AM has attracted research interest in chronic kidney disease (CKD) treatment. It functions by modulating the TGF-β/Smad and Wnt/β-catenin signaling pathways, which are crucial in renal fibrosis. Studies suggest it may also have protective effects on renal tubular epithelial cells. Due to its bioactivity and natural origin, it is considered a promising candidate for drug development in nephrology research.
| CAS Number | 151200-92-9 |
| Synonyms | (2R)-2-[(2R,3R,3aR,6S,7S,9bR)-2-hydroxy-6-(3-methoxy-3-oxopropyl)-3a,6,9b-trimethyl-7-prop-1-en-2-yl-1,2,3,4,7,8-hexahydrocyclopenta[a]naphthalen-3-yl]-6-methyl-5-methylideneheptanoic acid |
| Molecular Formula | C32H48O5 |
| Purity | ≥95% |
| IUPAC Name | (2R)-2-[(2R,3R,3aR,6S,7S,9bR)-2-hydroxy-6-(3-methoxy-3-oxopropyl)-3a,6,9b-trimethyl-7-prop-1-en-2-yl-1,2,3,4,7,8-hexahydrocyclopenta[a]naphthalen-3-yl]-6-methyl-5-methylideneheptanoic acid |
| InChI | InChI=1S/C32H48O5/c1-19(2)21(5)10-11-22(29(35)36)28-26(33)18-32(8)25-13-12-23(20(3)4)30(6,16-15-27(34)37-9)24(25)14-17-31(28,32)7/h13-14,19,22-23,26,28,33H,3,5,10-12,15-18H2,1-2,4,6-9H3,(H,35,36)/t22-,23+,26-,28+,30+,31-,32+/m1/s1 |
| InChIKey | WMPHZBWMRPCPKN-XNVOKYKKSA-N |
| SMILES | CC(C)C(=C)CC[C@H]([C@H]1[C@@H](C[C@@]2([C@@]1(CC=C3C2=CC[C@H]([C@]3(C)CCC(=O)OC)C(=C)C)C)C)O)C(=O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
