Pomalidomide-PEG4-COOH

• CAT Number: I025279
• CAS Number: 2138440-81-8
• Molecular Formula: C24H31N3O10
• Molecular Weight: 521.52
• Purity: ≥95%
• Synonyms: 3-[2-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
• InChI: InChI=1S/C24H31N3O10/c28-19-5-4-18(22(31)26-19)27-23(32)16-2-1-3-17(21(16)24(27)33)25-7-9-35-11-13-37-15-14-36-12-10-34-8-6-20(29)30/h1-3,18,25H,4-15H2,(H,29,30)(H,26,28,31)
• InChIKey: CAANPUBZFFRWQP-UHFFFAOYSA-N
• SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCOCCOCCC(=O)O

Pomalidomide-PEG4-COOH（Cat No.:I025279）is a derivative of pomalidomide, a potent immunomodulatory drug used primarily in the treatment of multiple myeloma. The addition of PEG4 (a polyethylene glycol linker) and a carboxylic acid group (COOH) enhances its pharmacokinetic properties, improving solubility, stability, and bioavailability. This modification allows for better drug delivery and targeted action. Pomalidomide itself works by modulating the immune system, promoting anti-tumor effects, and inhibiting angiogenesis. Pomalidomide-PEG4-COOH is used in research to develop more effective formulations or conjugates for cancer therapy and other immune-related diseases.