For research use only. Not for therapeutic Use.
Pomalidomide-C11-NH2 hydrochloride(CAT: I040591) is a functionalized immunomodulatory drug analog featuring a pomalidomide moiety linked via an 11-carbon alkyl chain to a terminal amine. The hydrochloride salt form enhances solubility and stability. This compound is ideal for conjugation applications, including targeted protein degradation studies such as PROTAC development. The extended linker allows spatial flexibility between the E3 ligase-binding pomalidomide and a target ligand, aiding bifunctional molecule design. Its structure supports diverse synthetic modifications, making it valuable in medicinal chemistry and chemical biology research focused on modulating protein homeostasis. Suitable for use in preclinical drug discovery and mechanism-of-action studies.
| CAS Number | 2722611-55-2 |
| Synonyms | 4-(11-aminoundecylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride |
| Molecular Formula | C24H35ClN4O4 |
| Purity | ≥95% |
| IUPAC Name | 4-(11-aminoundecylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride |
| InChI | InChI=1S/C24H34N4O4.ClH/c25-15-8-6-4-2-1-3-5-7-9-16-26-18-12-10-11-17-21(18)24(32)28(23(17)31)19-13-14-20(29)27-22(19)30;/h10-12,19,26H,1-9,13-16,25H2,(H,27,29,30);1H |
| InChIKey | DBBSXCXTLCVKLE-UHFFFAOYSA-N |
| SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCCCCCCCCCCN.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
