Pomalidomide-amino-PEG3-NH2 hydrochloride（Cat No.:I045305）is a functionalized pomalidomide derivative featuring a polyethylene glycol (PEG3) spacer terminated with a primary amine, supplied as a hydrochloride salt for improved stability and solubility. Pomalidomide acts as a cereblon (CRBN) ligand, enabling recruitment of the E3 ubiquitin ligase complex in targeted protein degradation strategies such as PROTACs. The PEG3 linker enhances molecular flexibility, solubility, and spatial orientation, facilitating efficient conjugation to target-binding ligands. This bifunctional building block is widely used in medicinal chemistry and chemical biology to design next-generation therapeutics based on selective protein degradation technology.