Poly(N-isopropylacrylamide) (PNiPAM)

  • CAT Number: M000068
  • CAS Number: 25189-55-3
  • Molecular Formula: C6H11NO
  • Molecular Weight: 113.16
  • Purity: ≥95%
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Poly(N-isopropylacrylamide) (PNiPAM)(Cat No.:M000068), is a temperature-responsive polymer with a wide range of applications in science and industry. At lower temperatures, PNiPAM is hydrophilic and water-soluble, but as the temperature increases, it becomes hydrophobic and precipitates out of the solution. This unique property has led to its use in drug delivery systems, tissue engineering, and smart materials. PNiPAM can form temperature-sensitive gels, making it valuable in controlled drug release and tissue culture.


Catalog Number M000068
CAS Number 25189-55-3
Synonyms

N-ISO-PROPYLACRYLAMIDE POLYMER;POLY(N-ISOPROPYL ACRYLAMIDE);2-Propenamide,N-(1-methylethyl)-,homopolymer;n-(1-methylethyl)-2-propenamidhomopolymer;poly(n-iso-propylacrylamide)(mw20000-25000);nipam polymer;2-Propenamid, N-(1-methylethyl)-, Homopolymer

Molecular Formula C6H11NO
Purity 0%
Solubility Soluble In THF, dioxane, DMF, cold water, chloroform
Storage -20°C
Related CAS 192708-92-2
IUPAC Name N-propan-2-ylprop-2-enamide
InChI InChI=1S/C6H11NO/c1-4-6(8)7-5(2)3/h4-5H,1H2,2-3H3,(H,7,8)
InChIKey QNILTEGFHQSKFF-UHFFFAOYSA-N
SMILES CC(C)NC(=O)C=C
Reference

1: Igwe IE, Zong Y, Yang X, Ouyang Z, Chen K. Induced Attraction between
Polystyrene Colloidal Particles in a Binary Mixture with PNIPAM Colloidal
Microgels. J Phys Chem B. 2017 May 17. doi: 10.1021/acs.jpcb.6b12999. [Epub ahead
of print] PubMed PMID: 28467075. <br />
2: Zajforoushan Moghaddam S, Thormann E. Hofmeister Effect on PNIPAM in Bulk and
at an Interface: Surface Partitioning of Weakly Hydrated Anions. Langmuir. 2017
May 16;33(19):4806-4815. doi: 10.1021/acs.langmuir.7b00953. Epub 2017 May 3.
PubMed PMID: 28448149. <br />
3: Yang M, Liu C, Lian Y, Zhao K, Zhu D, Zhou J. Relaxations and phase
transitions during the collapse of a dense PNIPAM microgel suspension-thorough
insight using dielectric spectroscopy. Soft Matter. 2017 Apr 5;13(14):2663-2676.
doi: 10.1039/c7sm00144d. PubMed PMID: 28332691. <br />
4: Sanz B, von Bilderling C, Tuninetti JS, Pietrasanta L, Mijangos C, Longo GS,
Azzaroni O, Giussi JM. Thermally-induced softening of PNIPAm-based nanopillar
arrays. Soft Matter. 2017 Mar 29;13(13):2453-2464. doi: 10.1039/c7sm00206h.
PubMed PMID: 28287232.

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