For research use only. Not for therapeutic Use.
Podophyllotoxin glucoside（Cat No.:R042053）is a derivative of podophyllotoxin, a naturally occurring compound with potent anticancer properties. It is a glycoside formed by attaching a glucose molecule to the podophyllotoxin structure, which enhances its solubility and bioavailability. Podophyllotoxin and its derivatives work by inhibiting the enzyme topoisomerase II, crucial for DNA replication, leading to cell cycle arrest and apoptosis in rapidly dividing cancer cells. Podophyllotoxin glucoside is studied for its potential in cancer therapy, particularly for treating tumors resistant to conventional therapies, by offering a more effective and bioavailable formulation.
| CAS Number | 16481-54-2 |
| Synonyms | (5R,5aR,8aR,9R)-5-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one |
| Molecular Formula | C28H32O13 |
| Purity | ≥95% |
| IUPAC Name | (5R,5aR,8aR,9R)-5-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one |
| InChI | InChI=1S/C28H32O13/c1-34-17-4-11(5-18(35-2)26(17)36-3)20-12-6-15-16(39-10-38-15)7-13(12)25(14-9-37-27(33)21(14)20)41-28-24(32)23(31)22(30)19(8-29)40-28/h4-7,14,19-25,28-32H,8-10H2,1-3H3/t14-,19+,20+,21-,22+,23-,24+,25-,28-/m0/s1 |
| InChIKey | NXVJTGLCCSFGAT-QNDDJFOYSA-N |
| SMILES | COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](C4=CC5=C(C=C24)OCO5)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
