Podocarpic acid

  • CAT Number: I004228
  • CAS Number: 5947-49-9
  • Molecular Formula: C17H22O3
  • Molecular Weight: 274.35
  • Purity: ≥95%
Inquiry Now

Podocarpic acid (CAT: I004228) is a naturally occurring compound that exhibits a wide range of positive effects. It is recognized as a novel activator of the TRPA1 (Transient Receptor Potential Ankyrin 1) channel. TRPA1 is a sensory receptor involved in pain and inflammation pathways. Podocarpic acid’s activation of TRPA1 suggests its potential in modulating pain perception and inflammatory responses. As a natural product, podocarpic acid holds promise as a valuable compound for further investigation and development in the field of pain management and potentially other therapeutic applications.

Catalog Number I004228
CAS Number 5947-49-9

12-hydroxypodocarpa-8,11,13-trien-16-oic acid;

Molecular Formula


Purity 95%
Target TRPA1
Solubility DMSO
Storage Room temperature
IUPAC Name (1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid
InChI InChI=1S/C17H22O3/c1-16-8-3-9-17(2,15(19)20)14(16)7-5-11-4-6-12(18)10-13(11)16/h4,6,10,14,18H,3,5,7-9H2,1-2H3,(H,19,20)/t14-,16-,17+/m1/s1

<p style=”/line-height:25px/”>
<br />
[1]. Baraka HN. Microbial transformation of podocarpic acid and evaluation of transformation products for antioxidant activity. Planta Med. 2010 May;76(8):815-7.<br />
[2]. Singh S, et al. Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2824-8.<br />
[3]. He W, et al. Novel cytokine release inhibitors. Part IV: analogs of podocarpic acid. Bioorg Med Chem Lett. 1999 Feb 8;9(3):469-74.<br />
[4]. Chaudhuri J, et al. A Caenorhabditis elegans Model Elucidates a Conserved Role for TRPA1-Nrf Signaling in Reactive &alpha;-Dicarbonyl Detoxification. Curr Biol. 2016 Nov 21;26(22):3014-3025.</p>

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!