PKG inhibitor peptide

• CAT Number: P000121
• CAS Number: 82801-73-8
• Molecular Formula: C38H74N18O10
• Molecular Weight: 943.11
• Purity: ≥95%
• Synonyms: (2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]pentanedioic acid
• InChI: InChI=1S/C38H74N18O10/c1-21(29(59)52-26(13-8-20-50-38(46)47)33(63)54-24(11-3-5-17-40)34(64)56-27(35(65)66)14-15-28(57)58)51-31(61)25(12-7-19-49-37(44)45)55-32(62)23(10-2-4-16-39)53-30(60)22(41)9-6-18-48-36(42)43/h21-27H,2-20,39-41H2,1H3,(H,51,61)(H,52,59)(H,53,60)(H,54,63)(H,55,62)(H,56,64)(H,57,58)(H,65,66)(H4,42,43,48)(H4,44,45,49)(H4,46,47,50)/t21-,22-,23-,24-,25-,26-,27-/m0/s1
• InChIKey: OUKSKNTVYYVIMZ-DUJSLOSMSA-N
• SMILES: C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)N

PKG Inhibitor Peptide（Cat No.:P000121）is a synthetic peptide specifically designed to inhibit protein kinase G (PKG), a serine/threonine kinase activated by cyclic GMP (cGMP). PKG plays a crucial role in smooth muscle relaxation, platelet function, and neuronal signaling. The inhibitor peptide typically mimics PKG substrates or regulatory domains, competitively blocking kinase activity. It is widely used in cardiovascular, neurological, and cell signaling research to dissect the role of cGMP-PKG pathways. The peptide form allows for selective, reversible inhibition, providing a valuable tool for studying PKG-mediated physiological and pathological processes in vitro and in vivo.