Pivampicillin

• CAT Number: I034850
• CAS Number: 33817-20-8
• Molecular Formula: C22H29N3O6S
• Molecular Weight: 463.549
• Purity: 98%
• Solubility: Soluble in DMSO
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (2S-(2alpha,5alpha,6beta(S*)))-
• InChI: InChI=1S/C22H29N3O6S/c1-21(2,3)20(29)31-11-30-19(28)15-22(4,5)32-18-14(17(27)25(15)18)24-16(26)13(23)12-9-7-6-8-10-12/h6-10,13-15,18H,11,23H2,1-5H3,(H,24,26)/t13?,14-,15+,18-/m1/s1
• InChIKey: ZEMIJUDPLILVNQ-KRWWSPQJSA-N
• SMILES: O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C(N)C3=CC=CC=C3)=O)N1C2=O)OCOC(C(C)(C)C)=O

Pivampicillin (Cat.No:I034850) is a pivalate ester analog of Ampicillin. It is used to treat chronic obstructive pulmonary disease (COPD) in children and young adults.

Reference

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3: Bukh N. Double-blind comparison of pivmecillinam plus pivampicillin (‘Miraxid’) with pivampicillin alone in chronic bronchitis: a Danish multi-centre study. Pharmatherapeutica. 1983;3(6):422-8. PubMed PMID: 6312461.
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20: Atkins MJ, Talbot DJ. A comparison of pivmecillinam/pivampicillin and amoxycillin in acute exacerbations of chronic bronchitis. J Int Med Res. 1987 Mar-Apr;15(2):115-20. PubMed PMID: 3556261.